Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • harvard-anglia-ruskin-university
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Costs and quality of life by disability among people with multiple sclerosis: a register-based study in Sweden
Karolinska Institutet / University of Gothenburg.ORCID-id: 0000-0001-6890-5162
Karolinska Institutet.ORCID-id: 0000-0003-3896-7332
Karolinska Institutet.
Karolinska Institutet / Karolinska University Hospital.
Visa övriga samt affilieringar
2018 (Engelska)Ingår i: Multiple sclerosis journal - experimental, translational and clinical, E-ISSN 2055-2173, Vol. 4, nr 3, artikel-id 2055217318783352Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: Population-based estimates of costs of illness and health-related quality of life, by disability levels among people with multiple sclerosis, are lacking.

Objectives: To estimate the annual costs of illness and health-related quality of life, by disability levels, among multiple sclerosis patients, 21-64 years of age.

Methods: Microdata from Swedish nationwide registers were linked to estimate the prevalence-based costs of illness in 2013, including direct costs (prescription drug use and specialised healthcare) and indirect costs (calculated using sick leave and disability pension), and health-related quality of life (estimated from the EQ-5D). Disability level was measured by the Expanded Disability Status Scale (EDSS).

Results: Among 8906 multiple sclerosis patients, EDSS 0.0-3.5 and 7.0-9.5 were associated with mean indirect costs of SEK 117,609 and 461,357, respectively, whereas direct costs were similar between the categories (SEK 117,423 and 102,714, respectively). Prescription drug costs represented 40% of the costs of illness among multiple sclerosis patients with low EDSS, while among patients with high EDSS more than 80% were indirect costs. Among the 1684 individuals who had reported both EQ-5D and EDSS, the lowest health-related quality of life scores were found among those with a high EDSS.

Conclusion: Among people with multiple sclerosis, we confirmed higher costs and lower health-related quality of life in higher disability levels, in particular high indirect costs.

Ort, förlag, år, upplaga, sidor
2018. Vol. 4, nr 3, artikel-id 2055217318783352
Nyckelord [en]
Multiple sclerosis, cost of illness, disability evaluation, disease progression, health-related quality of life, healthcare costs, registries, sick leave
Nationell ämneskategori
Omvårdnad
Identifikatorer
URN: urn:nbn:se:rkh:diva-2611DOI: 10.1177/2055217318783352PubMedID: 30090640OAI: oai:DiVA.org:rkh-2611DiVA, id: diva2:1243160
Forskningsfinansiär
Forte, Forskningsrådet för hälsa, arbetsliv och välfärd, 2007-1762Tillgänglig från: 2018-08-30 Skapad: 2018-08-30 Senast uppdaterad: 2018-09-03Bibliografiskt granskad

Open Access i DiVA

fulltext(577 kB)122 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 577 kBChecksumma SHA-512
5cd6fcb1cc7b9af2adece4af1654ec23f52b988e85e72888c020e683d9cb6c79204baa80fa631e1f7a0b2d6eb752881628926b1d82c1f0d5249b850edc776f39
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Tinghög, Petter

Sök vidare i DiVA

Av författaren/redaktören
Gyllensten, HannaKavaliunas, AndriusTinghög, Petter
Av organisationen
Hälsovetenskapliga institutionen
Omvårdnad

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 122 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 69 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • harvard-anglia-ruskin-university
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf