Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • harvard-anglia-ruskin-university
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Heredity, pet ownership, and confounding control in a population-based birth cohort
The Department of Occupational and Environmental Health, Karolinska Hospital, Stockholm.
The Department of Occupational and Environmental Health, Karolinska Hospital, Stockholm.ORCID-id: 0000-0003-2504-343X
The Department of Medicine, Unit of Clinical Immunology and Allergy, Karolinska Institutet, Stockholm.
The Department of Occupational and Environmental Health, Karolinska Hospital, Stockholm.
Visa övriga samt affilieringar
2003 (Engelska)Ingår i: Journal of Allergy and Clinical Immunology, ISSN 0091-6749, E-ISSN 1097-6825, Vol. 111, nr 4, s. 800-806Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND: The association between pet ownership in childhood and subsequent allergic disease is controversial. Bias related to selection of pet exposure has been suggested as a reason for contradictory study results.

OBJECTIVE: The purpose of this investigation was to elucidate how pet exposure depends on family history of allergic disease, smoking, and socioeconomic factors in a prospective birth cohort.

METHODS: Parents of 4089 two-month-old children answered a questionnaire that included detailed questions about family history of asthma (maternal, paternal, and sibling), rhinoconjunctivitis, atopic eczema/dermatitis syndrome, pollen and pet allergy, smoking habits, parental occupation, and family pet ownership (cat and dog). Dust samples collected from the mothers' beds were analyzed for Fel d 1 and Can f 1 in a subgroup of the cohort.

RESULTS: Cats were less frequently kept in families with parental asthma, rhinoconjunctivitis, or pet or pollen allergy (3.5% to 5.8%) than in families without parental allergic disease (10.8% to 11.8%). Dogs were less common in families with (3.3%) than in families without (5.9%) parental atopic eczema/dermatitis syndrome. Families with smoking mothers and those with low socioeconomic index kept cats and dogs more frequently. Cat allergen levels were lower in homes with than in homes without maternal pet allergy, and this tended to hold true even for homes without a cat. Cat ownership decreased from birth to 2 years of age, especially in families with parental history of allergic diseases.

CONCLUSION: There seems to be a selection of pet exposure based on parental history of allergy, maternal smoking, and socioeconomic factors. This has to be taken into consideration in evaluations of risk associations between pet exposure and allergic disease in childhood.

Ort, förlag, år, upplaga, sidor
Elsevier, 2003. Vol. 111, nr 4, s. 800-806
Nyckelord [en]
asthma, cats, dogs, allergens, Fel d 1, Can f 1, heredity, primary prevention, confounding factors, prospective studies
Nationell ämneskategori
Medicin och hälsovetenskap Lungmedicin och allergi
Identifikatorer
URN: urn:nbn:se:rkh:diva-602DOI: 10.1067/mai.2003.1334PubMedID: 12704361OAI: oai:DiVA.org:rkh-602DiVA, id: diva2:610543
Tillgänglig från: 2013-03-12 Skapad: 2013-03-11 Senast uppdaterad: 2017-12-06Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Egmar, Ann-Charlotte

Sök vidare i DiVA

Av författaren/redaktören
Egmar, Ann-Charlotte
I samma tidskrift
Journal of Allergy and Clinical Immunology
Medicin och hälsovetenskapLungmedicin och allergi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 429 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • harvard-anglia-ruskin-university
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf