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Hypoventilation does not explain the impaired quality of sleep in postpolio patients ventilated noninvasively vs. invasively
Röda Korsets Högskola. Karolinska Institutet.
National Respiratory Center, Division of Anaesthesiology and Intensive Care, Department of Clinical Sciences, Karolinska Institutet at Danderyd Hospital, Stockholm, Sweden.
National Respiratory Center, Division of Anaesthesiology and Intensive Care, Department of Clinical Sciences, Karolinska Institutet at Danderyd Hospital, Stockholm, Sweden.
National Respiratory Center, Division of Anaesthesiology and Intensive Care, Department of Clinical Sciences, Karolinska Institutet at Danderyd Hospital, Stockholm, Sweden.
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2008 (Engelska)Ingår i: Scandinavian Journal of Caring Sciences, ISSN 0283-9318, E-ISSN 1471-6712, Vol. 22, nr 2, s. 236-240Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

In a previous study, it was found that patients treated with noninvasive ventilation (NIV) reported larger dysfunctions in sleep-related parameters as assessed with the Sickness Impact Profile (SIP) and Health Index questionnaires than those treated with tracheostomy. The aim of the current study was to further evaluate these sleep limitations and relate these limitations to blood gas analyses in the groups to investigate, if the differences could be related to differences in the efficacy of ventilation. We compared postpolio patients treated with tracheostomy (PPT, n = 17), NIV (PPN, n = 14) and patients with neuromuscular disorders treated with NIV (NMN, n = 15). Significantly fewer patients in the PPT group scored large dysfunctions in the SIP sleep (SIP score >10 points) compared with the PPN and NMN patients. The PPT patients scored significantly higher regarding quality of sleep and less sense of tiredness than the PPN and NMN patients. No differences were found between the groups regarding blood gas parameters neither before nor during or after the study period. In conclusion, postpolio patients treated with invasive home mechanical ventilation seem to experience better sleep and less sense of tiredness than patients on NIV. These differences cannot be explained by differences in alveolar ventilation as assessed with blood gas analyses.

Ort, förlag, år, upplaga, sidor
2008. Vol. 22, nr 2, s. 236-240
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URN: urn:nbn:se:rkh:diva-1129DOI: 10.1111/j.1471-6712.2007.00520.xPubMedID: 18489694OAI: oai:DiVA.org:rkh-1129DiVA, id: diva2:759391
Tillgänglig från: 2014-10-29 Skapad: 2014-10-21 Senast uppdaterad: 2017-12-05Bibliografiskt granskad

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