Digitization exceeds the limits of healthcare meetings, which gives renewed relevance to examine the collaboration between engineers and nurses. Caring for people is no longer just something going on in the hospital but at new arenas at home and in the middle of people's everyday lives. In caring situations nurse's responsibility is, unlike the physician, to make observations and to follow in detail the patient's caring needs, and where engineers provide technological devices to support and monitor the course of the disease. When digitizing the caring situation person-centered care gets a new meaning. For engineers the understanding of how technology is contextualized and domesticated becomes even more important to make applications and systems work outside laboratories. This paper presents two cases of interaction between engineers and nurses aimed at improving the implementation of robots and sensorsin elderly people ́s homes; and learning how to improve patient safety in hospitals.The result shows that conflicting epistemologies, differences in professional languages and lack of joint learning opportunities are factors that create obstacles for interactions. The conclusionsreject the idea of linear innovation processes and showthat successful ccollaborationtake more than just adding two and two together. Especially digitization is breaking up traditional barriers and hierarchies. For nurses to be proactive requires knowledge about technological developments and the ability toparticipate in design and innovation processes. For engineers a more thorough understanding of caring situations and users will contribute to a more reliable provision of digitalsolutions and point at new ideas leading up to innovations. The main output of the paper is that it is deepening the understanding of what factors leading to successfulcollaborations between nursing and engineering and what are the missing links.