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Effects of exercise in non-treatment seeking adults with alcohol use disorder: A three-armed randomized controlled trial (FitForChange)
Department of Public Health Sciences, Karolinska Institutet; Department of Clinical Neuroscience, Karolinska Institutet.
Department of Public Health Sciences, Karolinska Institutet; Department of Clinical Neuroscience, Karolinska Institutet.
Swedish Red Cross University, Department of Health Sciences. Department of Neurobiology, Care Sciences and Society, Karolinska Institutet.ORCID iD: 0000-0003-4570-4047
Swedish School of Sport and Health Science (GIH).
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2022 (English)In: Drug And Alcohol Dependence, ISSN 0376-8716, E-ISSN 1879-0046, Vol. 232, article id 109266Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Most individuals with alcohol use disorder (AUD) do not seek treatment. Stigma and the desire to self-manage the problem are likely explanations. Exercise is an emerging treatment option but studies in non-treatment seeking individuals are lacking. We compared the effects of aerobic exercise, yoga, and treatment as usual (phone-based support) on alcohol consumption in non-treatment seeking adults with AUD.

METHODS: Three-group parallel, single blind, randomized controlled trial. 140 physically inactive adults aged 18-75 diagnosed with AUD were included in this community-based trial. Participants were randomized to either aerobic exercise (n = 49), yoga (n = 46) or treatment as usual (n = 45) for 12-weeks. The primary study outcome was weekly alcohol consumption at week 13 (Timeline Follow-back).

RESULTS: A significant decrease in weekly alcohol consumption was seen in all three groups: aerobic exercise (mean ∆ = - 5.0, 95% C = - 10.3, - 3.5), yoga group (mean ∆ = - 6.9, 95% CI = - 10.3, - 3.5) and TAU (mean ∆ = - 6.6, 95% CI = - 8.8, - 4.4). The between group changes were not statistically significant at follow-up. Per-protocol analyzes showed that the mean number of drinks per week reduced more in both TAU (mean ∆ = - 7.1, 95% CI = - 10.6, - 3.7) and yoga (mean ∆ = - 8.7, 95% CI = - 13.2, - 4.1) compared to aerobic exercise (mean ∆ = - 1.7, 95% CI = - 4.4, 1. 0), [F(2, 55) = 4.9, p = 0.011].

CONCLUSIONS: Participation in a 12-week stand-alone exercise program was associated with clinically meaningful reductions in alcohol consumption comparable to usual care (phone counseling) by an alcohol treatment specialist.

Place, publisher, year, edition, pages
Elsevier, 2022. Vol. 232, article id 109266
Keywords [en]
Aerobic exercise, Alcohol use disorder, Randomized controlled trial, Treatment, Yoga
National Category
Public Health, Global Health, Social Medicine and Epidemiology Nursing
Identifiers
URN: urn:nbn:se:rkh:diva-4182DOI: 10.1016/j.drugalcdep.2022.109266PubMedID: 35033949OAI: oai:DiVA.org:rkh-4182DiVA, id: diva2:1629531
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare, 2016- 07113Ekhaga Foundation, 2018-0042Available from: 2022-01-18 Created: 2022-01-18 Last updated: 2022-04-05Bibliographically approved

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Jirwe, Maria

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