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Risk factors for psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment
Uppsala universitet, Institutionen för kvinnors och barns hälsa. (Klinisk och experimentell reproduktionsbiologi/Olovsson)
Uppsala universitet, Institutionen för kvinnors och barns hälsa. (Klinisk och experimentell reproduktionsbiologi/Olovsson)
Uppsala universitet, Psykiatri, Akademiska sjukhuset.
Uppsala universitet, Institutionen för kvinnors och barns hälsa. (Klinisk och experimentell reproduktionsbiologi/Olovsson)
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2010 (English)In: Fertility and Sterility, ISSN 0015-0282, E-ISSN 1556-5653, Vol. 93, no 4, 1088-1096 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To identify risk factors associated with depression and anxiety in infertile women and men undergoing in vitro fertilization (IVF). DESIGN: Prospective study. SETTING: A university hospital in Sweden during a 2-year period. PATIENT(S): 825 participants (413 women and 412 men). INTERVENTION(S): Primary Care Evaluation of Mental Disorders (PRIME-MD), based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), as the diagnostic tool for evaluating mood and anxiety disorders, and fertility history and outcome of IVF treatment collected from the patients' medical records. MAIN OUTCOME MEASURE(S): Risk factors associated with depression and anxiety disorders. RESULT(S): A negative pregnancy test and obesity were the independent risk factors for any mood disorders in women. Among men, the only independent risk factor for depression was unexplained infertility. No IVF-related risk factors could be identified for any anxiety disorder. CONCLUSION(S): A negative pregnancy test is associated with an increased risk for depression in women undergoing IVF, but no risk of developing anxiety disorders is associated with the pregnancy test result after IVF. Pregnancy test results were not a risk factor for depression or anxiety among men.

Place, publisher, year, edition, pages
Elsevier, 2010. Vol. 93, no 4, 1088-1096 p.
Keyword [en]
Depression, anxiety, women, men, infertility, in vitro fertilization, risk factors
National Category
Medical and Health Sciences Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:rkh:diva-1103DOI: 10.1016/j.fertnstert.2008.11.008PubMedID: 19118826OAI: oai:DiVA.org:rkh-1103DiVA: diva2:754399
Available from: 2009-05-13 Created: 2014-10-10 Last updated: 2014-10-10Bibliographically approved

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Volgsten, HelenaLundkvist, Örjan
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