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  • 1.
    Craftman, Åsa Gransjön
    et al.
    Sophiahemmet University; Aging Research Center (ARC), Karolinska Institutet.
    Johnell, Kristina
    Aging Research Center (ARC), Karolinska Institutet.
    Fastbom, Johan
    Aging Research Center (ARC), Karolinska Institutet.
    Westerbotn, Margareta
    Department of Research, Education, Development and Innovation, Education Center, SÖS.
    von Strauss, Eva
    The Swedish Red Cross University College, Department of Public Health and Medicine. Aging Research Center (ARC), Karolinska Institutet.
    Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden.2015In: Archives of gerontology and geriatrics (Print), ISSN 0167-4943, E-ISSN 1872-6976, Vol. 63, p. 28-35Article in journal (Refereed)
    Abstract [en]

    New drugs and expanded drug indications are constantly being introduced. Welfare states strive to provide equity in drug treatment for all of its citizens and todaýs healthcare systems spend financial resources on drugs for the elderly in a higher rate than for any other age group. Drug utilization in elderly persons has an impact in health and wellbeing in older people.

    THE PURPOSE OF THE RESEARCH: It was to describe the changes in medication use including people aged 78 years and over regardless of residence and other characteristics over 20 years.

    MATERIALS AND METHODS: The study population consisted of 4304 participants in three population-based cross-sectional surveys conducted in the Kungsholmen area of central Stockholm, Sweden. The participant's current drug utilization was reviewed by physicians following standardized protocols. Data were statistical analyzed. Logistic regression models was used to estimate odds ratios and 95% confidence intervals for use of analgesics and psychotropic drugs in the cohorts of 2001 and 2007, controlling for age, gender, education and cognition.

    THE PRINCIPAL RESULTS AND MAJOR CONCLUSIONS: Results shows that the prevalence of medication use and polypharmacy in older adults has increased dramatically the late 1980s to the 2000s in central Stockholm, Sweden. In particular, the use of analgesics increased significantly, while some drug groups decreased, i.e., antipsychotics. Women used more medication than men in all three cohorts. Older adults living in service buildings used the largest amount of drugs in 1987, whereas those living in institutions were the most frequent users in 2001 and 2007.

  • 2.
    Karp, Anita
    et al.
    Neurotec, Karolinska Institutet.
    Paillard-Borg, Stéphanie
    Neurotec, Karolinska Institutet.
    Wang, Hui-Xin
    Neurotec, Karolinska Institutet.
    Silverstein, Merril
    niversity of Southern California, Andrus Gerontology Center, Los Angeles, CA, USA.
    Winblad, Bengt
    Neurotec, Karolinska Institutet.
    Fratiglioni, Laura
    Neurotec, Karolinska Institutet.
    Mental, physical, and social components in common leisure activities in old age in relation to dementia: Findings from the Kungsholmen Project2004In: Neurobiology of Aging, ISSN 0197-4580, E-ISSN 1558-1497, Vol. 25, p. S313-Article in journal (Other academic)
  • 3.
    Sjölund, Britt-Marie
    et al.
    Aging Research Center (ARC), Karolinska Institutet-Stockholm University.
    Wimo, Anders
    Aging Research Center (ARC), Karolinska Institutet-Stockholm University.
    Qiu, Chengxuan
    Aging Research Center (ARC), Karolinska Institutet-Stockholm University.
    Engström, Maria
    University of Gävle.
    von Strauss, Eva
    The Swedish Red Cross University College. Aging Research Center (ARC), Karolinska Institutet-Stockholm University.
    Time trends in prevalence of activities of daily living (ADL) disability and survival: Comparing two populations (aged 78+ years) living in a rural area in Sweden2014In: Archives of gerontology and geriatrics (Print), ISSN 0167-4943, E-ISSN 1872-6976, Vol. 58, no 3, p. 370-375Article in journal (Refereed)
    Abstract [en]

    The aim was to study time trends in prevalence of disability in ADL and survival among men and women 78 years and older comparing two cohorts. The study was a time trend study based on two population-based community cohorts, the Nordanstig Project (NP), collected 1995–1998 and the Swedish National Study on Aging and Care in Nordanstig (SNAC-N), collected 2001–2003. The participants were people aged 78 years and older from the NP cohort (N = 303) and from the SNAC-N cohort (N = 406). All were clinically examined by physicians and nurses using standardized protocols. Disability was defined as a need for assistance in one or more ADL activities. The prevalence of disability and survival were compared using logistic and Cox models. The prevalence of ADL disability was stable for men, while women became more disabled in ADL during the time period, OR 2.36 (1.12–4.94). There was no significant difference in survival time between the cohorts in either ADL disabled persons or non-disabled persons. There was a tendency for increased survival for non-disabled persons in SNAC-N compared with NP, although not significant; this was particularly true for women. In general, women survived longer than men did regardless of whether they were ADL disabled or not. The time trends for ADL disability found in the study show that ADL disability had increased in women but not in men. More studies are needed to identify risk factors for ADL disability with a view to preventing it in time.

  • 4.
    von Strauss, Eva
    et al.
    Karolinska instiutet.
    Backman, L
    Herlitz, A
    Fastbom, J
    Winblad, B
    Fratiglioni, L
    Physical and mental functioning in a population over 60 years of age. Data from the SNAC-Kungsholmen Project2005In: International psychogeriatrics, ISSN 1041-6102, E-ISSN 1741-203X, Vol. 17, no supl 2, p. 213-214Article in journal (Refereed)
  • 5.
    Wang, Hui-Xin
    et al.
    Karolinska Institutet.
    Paillard-Borg, Stéphanie
    Karolinska Institutet.
    Winblad, Bengt
    Karolinska Institutet.
    Fratiglioni, Laura
    Karolinska Institutet.
    Physical activity, emotional support, and intellectual stimulation in relation to dementia risk in the elderly: Results from the Kungsholmen Project2002In: Neurobiology of Aging, ISSN 0197-4580, E-ISSN 1558-1497, Vol. 23, no 1, p. S289-Article in journal (Other academic)
1 - 5 of 5
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