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  • 1. Qiu, CX
    et al.
    von Strauss, Eva
    Winblad, B
    Fratiglioni, L
    Decline in blood pressure over time and risk of dementia in the Kungsholmen project2004In: International Journal of Psychology, ISSN 0020-7594, E-ISSN 1464-066X, Vol. 39, no 5-6 Suppl. S, p. 175-175Article in journal (Refereed)
    Abstract [en]

    Aim-To examine the relationship between blood pressure decline and dementia risk. Methods-A community-based dementia-free cohort (n=947, 75+ years) was followed to detect dementia. Data were analyzed with Cox models. Results-Blood pressure markedly decreased before dementia diagnosis and continued to decline thereafter. Diastolic pressure decline was not predictive of dementia. Systolic pressure decline ⩾15 mm Hg was associated with an increased risk of dementia among people with baseline systolic pressure <160 mm Hg. Conclusions-Blood pressure decreases from the preclinical phase of dementia. A greater decline in systolic pressure is associated with dementia risk in selective subgroups of aging population.

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