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  • 1.
    Agüero-Torres, H
    et al.
    Stockholm Gerontology Research Center, Karolinska Institute.
    Fratiglioni, L
    Guo, Z
    Viitanen, M
    von Strauss, Eva
    Winblad, B
    Dementia is the major cause of functional dependence in the elderly: 3-year follow-up data from a population-based study1998In: American Journal of Public Health, ISSN 0090-0036, E-ISSN 1541-0048, Vol. 88, no 10, p. 1452-1456Article in journal (Refereed)
    Abstract [en]

    OBJECTIVES: The purpose of this investigation was to study the role of dementia and other common age-related diseases as determinants of dependence in activities of daily living (ADL) in the elderly. METHODS: The study population consisted of 1745 persons, aged 75 years and older, living in a district of Stockholm. They were examined at baseline and after a 3-year follow-up interval. Katz's index was used to measure functional status. Functional dependence at baseline, functional decline, and development of functional dependence at follow-up were examined in relation to sociodemographic characteristics and chronic conditions. RESULTS: At baseline, factors associated with functional dependence were age, dementia, cerebrovascular disease, heart disease, and hip fracture. However, only age and dementia were associated with the development of functional dependence and decline after 3 years. In a similar analysis, including only nondemented subjects. Mini-Mental State Examination scores emerged as one of the strongest determinants. The population attributable risk percentage of dementia in the development of functional dependence was 49%. CONCLUSIONS: In a very old population, dementia and cognitive impairment make the strongest contribution to both the development of long-term functional dependence and decline in function.

  • 2.
    Ervasti, Jenni
    et al.
    Finnish Institute of Occupational Health, Helsinki and Turku, Finland.
    Virtanen, Marianna
    Finnish Institute of Occupational Health, Helsinki and Turku, Finland.
    Pentti, Jaana
    Finnish Institute of Occupational Health, Helsinki and Turku, Finland.
    Lallukka, Tea
    Finnish Institute of Occupational Health, Helsinki and Turku, Finland.
    Tinghög, Petter
    Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet.
    Kjeldgard, Linnea
    Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet.
    Mittendorfer-Rutz, Ellenor
    Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet.
    Alexanderson, Kristina
    Division of Insurance Medicine,Department of Clinical Neuroscience, Karolinska Institutet.
    Work disability before and after diabetes diagnosis: a nationwide population-based register study in Sweden.2015In: American Journal of Public Health, ISSN 0090-0036, E-ISSN 1541-0048, Vol. 105, no 6, p. e22-e29Article in journal (Refereed)
    Abstract [en]

    OBJECTIVES: We evaluated the risk of work disability (sick leave and disability pension) before and after diabetes diagnosis relative to individuals without diabetes during the same time period, as well as the trajectory of work disability around the diagnosis.

    METHODS: This Swedish population-based cohort study with register data included 14 428 individuals with incident diabetes in 2006 and 39 702 individuals without diabetes during 2003 to 2009.

    RESULTS: Work disability was substantially higher among people with diabetes (overall mean = 95 days per year over the 7 years, SD = 143) than among those without diabetes (mean = 35 days, SD = 95). The risk of work disability was slightly higher after diabetes diagnosis than before and compared with the risk of those without diabetes. The trajectory of work disability was already increasing before diagnosis, increased even more at the time of diagnosis, and leveled off after diagnosis. Individual sociodemographic characteristics and comorbid conditions contributed both to the risk and to the trajectory of work disability.

    CONCLUSIONS: Although diabetes has an independent effect on work disability, sex, age, education, and comorbid conditions play a significant role.

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