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  • 1.
    Egmar, Ann-Charlotte
    et al.
    Department of Environmental Health, Stockholm County Council, Stockholm.
    Almqvist, C
    Department of Environmental Health, Stockholm County Council, Stockholm.
    Emenius, G
    Department of Environmental Health, Stockholm County Council, Stockholm.
    Lilja, G
    Department of Environmental Health, Stockholm County Council, Stockholm.
    Wickman, M
    Department of Environmental Health, Stockholm County Council, Stockholm.
    Deposition of cat (Fel d 1), dog (Can f 1), and horse allergen over time in public environments--a model of dispersion1998In: Allergy. European Journal of Allergy and Clinical Immunology, ISSN 0105-4538, E-ISSN 1398-9995, Vol. 53, no 10, p. 957-961Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: The occurrence and accumulation over time in public environments of cat, dog, and horse allergens was evaluated.

    METHODS: Concentrations of animal danders were analyzed by ELISA and countercurrent immunoelectrophoresis (CCIE).

    RESULTS: Among factory-new mattresses, 15/17 contained detectable levels of cat and/or dog allergen, whereas no horse allergen was found although six of the mattresses were stuffed with horsehair. Dust from 15 used mattresses contained significantly higher concentrations of Fe1 d 1 and Can f 1 than the factory-new ones (P < 0.001). Allergen concentrations and titers correlated to the period of time that the mattresses had been tried by customers; rs = 0.52-0.77, P = 0.04-0.001 (cat), rs = 0.38-0.48, P = 0.15-0.08 (dog), and rs = 0.64-0.74, P = 0.008-0.003 (horse). The increase over time occurred rapidly in highly frequented stores and after 3 weeks reached concentrations that have been found in homes where furred pets had formerly been kept or even the lower allergen scale of homes where pets were currently kept.

    CONCLUSIONS: The dispersion of allergens from furred animals to pet-free public places is likely to occur by deposition from people who have been in direct or indirect contact with pets, and high levels of such allergens seem to accumulate in a short period of time.

  • 2.
    Jonsson, M.
    et al.
    Department of Womans and Childrens Health, Karolinska Institutet / Centre of Occupational and Environmental Medicine, Stockholm County Counsil.
    Bergström, A.
    Karolinska Institutet, Institute of Environmental Medicine.
    Egmar, Ann-Charlotte
    Red Cross University College of Nursing. Department of Learning, Informatics, Management and Ethics, Medical Management Centre, Karolinska Institutet.
    Wickman, M.
    Karolinska Institutet, Institute of Environmental Medicine / Sachs’ Children's Hospital, Södersjukhuset.
    Lind, T.
    Centre of Occupational and Environmental Medicine, Stockholm County Counsil / Karolinska Institutet, Institute of Environmental Medicine.
    Kull, I
    Karolinska Institutet, Institute of Environmental Medicine / Sachs’ Children's Hospital, Södersjukhuset / Department of Clinical Science and Education, Stockholm South General Hospital, Karolinska Institutet.
    Health related quality of life among adolescents with asthma2014In: Allergy. European Journal of Allergy and Clinical Immunology, ISSN 0105-4538, E-ISSN 1398-9995, Vol. 69, no Suppl. 99: SI, p. 328-328Article in journal (Other academic)
  • 3.
    Ostblom, E
    et al.
    Department of Pediatrics, Sachs’ Children’s Hospital.
    Egmar, Ann-Charlotte
    Department of Occupational and Environmental Health, Stockholm County Council.
    Gardulf, A
    Department of Laboratory Medicine, Section of Clinical Immunology, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm.
    Lilja, G
    Department of Pediatrics, Sachs’ Children’s Hospital.
    Wickman, M
    Department of Pediatrics, Sachs’ Children’s Hospital.
    The impact of food hypersensitivity reported in 9-year-old children by their parents on health-related quality of life2008In: Allergy. European Journal of Allergy and Clinical Immunology, ISSN 0105-4538, E-ISSN 1398-9995, Vol. 63, no 2, p. 211-218Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: There are only a few studies on the impact of food hypersensitivity (FHS) in children on health-related quality of life (HRQL). The present study was designed to examine this impact in a population-based birth cohort (BAMSE).

    METHODS: A nested case-control study was performed within the cohort. The parents of 1378 nine-year-old children filled out a generic questionnaire with 13 subscales (Child Health Questionnaire Parental Form 28 - CHQ-PF28) supplemented with disease-specific questions concerning FHS. There were 212 children with report of FHS. Another 221 children with allergic diseases but not FHS were examined for comparison. Furthermore, the impact of pronounced symptoms of FHS and of increasing levels of food-specific IgE antibodies on HRQL was also analysed.

    RESULTS: The children with FHS exhibited significantly lower scores on the subscales physical functioning, role/social limitations - physical and general health in the generic instrument. Furthermore, children with food-related symptoms from the lower airways were scored lower on Self Esteem, Parental Impact - time and Family Cohesion. Sensitization per se did not alter these patterns, but high levels of food-specific IgE-antibodies affected mental health and general health negatively. A physician's diagnosis of food allergy did not affect any of the subscales negatively.

    CONCLUSIONS: Parents reported that FHS exerts a negative impact on the HRQL of 9-year-old children, in particular in children with symptoms from the lower airways or if the FHS is associated with high levels of food-specific IgE-antibodies. Healthcare-givers must put major effort into improving and maintaining the HRQL of these children.

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