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  • 1.
    Volgsten, Helena
    et al.
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Skoog Svanberg, Agneta
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Ekselius, Lisa
    Uppsala universitet, Institutionen för neurovetenskap.
    Lundkvist, Örjan
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Sundström Poromaa, Inger
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment2008In: Human Reproduction, ISSN 0268-1161, E-ISSN 1460-2350, Vol. 23, no 9, p. 2056-2063Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: This study was undertaken to determine the prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization (IVF) treatment. METHODS: Participants were 1090 consecutive women and men, 545 couples, attending a fertility clinic in Sweden during a two-year period. The Primary Care Evaluation of Mental Disorders (PRIME-MD), based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edn (DSM-IV), was used as the diagnostic tool for evaluating mood and anxiety disorders. RESULTS: Overall, 862 (79.1%) subjects filled in the PRIME-MD patient questionnaire. Any psychiatric diagnosis was present in 30.8% of females and in 10.2% of males in the study sample. Any mood disorder was present in 26.2% of females and 9.2% of males. Major depression was the most common mood disorder, prevalent in 10.9% of females and 5.1% of males. Any anxiety disorder was encountered in 14.8% of females and 4.9% males. Only 21% of the subjects with a psychiatric disorder according to DSM-IV received some form of treatment. CONCLUSIONS: Mood disorders are common in both women and men undergoing IVF treatment. The majority of subjects with a psychiatric disorder were undiagnosed and untreated.

  • 2.
    Volgsten, Helena
    et al.
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Skoog Svanberg, Agneta
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Ekselius, Lisa
    Uppsala universitet, Psykiatri, Akademiska sjukhuset.
    Lundkvist, Örjan
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Sundström Poromaa, Inger
    Uppsala universitet, Institutionen för kvinnors och barns hälsa.
    Risk factors for psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment2010In: Fertility and Sterility, ISSN 0015-0282, E-ISSN 1556-5653, Vol. 93, no 4, p. 1088-1096Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE: To identify risk factors associated with depression and anxiety in infertile women and men undergoing in vitro fertilization (IVF). DESIGN: Prospective study. SETTING: A university hospital in Sweden during a 2-year period. PATIENT(S): 825 participants (413 women and 412 men). INTERVENTION(S): Primary Care Evaluation of Mental Disorders (PRIME-MD), based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), as the diagnostic tool for evaluating mood and anxiety disorders, and fertility history and outcome of IVF treatment collected from the patients' medical records. MAIN OUTCOME MEASURE(S): Risk factors associated with depression and anxiety disorders. RESULT(S): A negative pregnancy test and obesity were the independent risk factors for any mood disorders in women. Among men, the only independent risk factor for depression was unexplained infertility. No IVF-related risk factors could be identified for any anxiety disorder. CONCLUSION(S): A negative pregnancy test is associated with an increased risk for depression in women undergoing IVF, but no risk of developing anxiety disorders is associated with the pregnancy test result after IVF. Pregnancy test results were not a risk factor for depression or anxiety among men.

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